Sensitive Dependence of Mental Function on Prefrontal Cortex

Compelling data suggest higher mental functions, executive function, awareness, consciousness, planning, strategic thinking, imagination and processing sensory input are the domain of prefrontal cortex function and in particular Brodman areas 8, 9, 10, 46 [1,2]. Recent studies have also suggested that the mediating influence of prefrontal cortex function is crucial in depression and in antidepressant strategies [3] is it possible that what is true for depression may also be true for other psychiatric disorders? And if this is true, does that suggest that prefrontal cortex is endowed with a unique mediating influence of mood, normalcy and psychiatric illness? And does this suggest that a small decline of prefrontal cortex influence may have large effects in brain function and human behavior similar to the butterfly effect of complex systems?